Extracellular vesicles (EVs) play key roles in cell-to-cell communication. EVs can cross biological barriers (such as the blood-brain barrier) and get internalized into the cell with a high degree of specificity.
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Infectious diseases are caused by pathogenic microorganisms such as bacteria, viruses, fungi or prions. Super-resolution microscopy helps find more efficient ways of diagnosing, treating and preventing them.
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Understanding brain structure and function at a single-molecule level is key for understanding the molecular mechanisms underlying neurodegenerative disorders and improve early disease diagnosis.
Learn MoreUntil recently, due to their size and design, the majority of super-resolution microscopes have not been able to support research in enclosed, ventilated biosafety cabinets. But things are changing.
View Case StudyVisualize and track EVs in solution or within cells to understand their behaviour.
View Case StudyViral particles vary greatly in size, but are typically below the resolution limit of conventional light microscopy. Recently, super-resolution techniques have been employed to study their mechanistic and functional characteristics at a single-molecule level.
View Case StudyBy helping researchers to unravel new, dynamic information about virus particles, super-resolution micoscopy enables breakthroughs in the understanding of viral pathogens and in finding new targets to treat viral infection.
View Case StudySuper-resolution imaging can be used to study fine morphological details and precise localization of EV-associated proteins.
View Case StudyThe Nanoimager can track single molecules and vesicles in both bacterial and eukaryotic cells with super-resolution microscopy.
View Case StudyGain detailed understanding of cellular features through multi-color super-resolution microscopy with advanced data analysis including colocalization and clustering.
View Case StudyIntensity measurements, super-resolution and multi-color labeling for characterizing protein complexes and their assembly.
View Case StudyUsing smFRET to understand molecular interactions and dynamics, including enzymes and substrates, protein aggregates in neurodegeneration and other protein-protein interactions.
View Case StudyA dynamic, real-time nanoscale ruler, now a general tool for characterizing molecular interactions and structure with Alternating Laser Excitation (ALEX) support.
View Case StudyImaging specific target sites on DNA at the single-molecule level: a simple tool for characterizing the distribution of epigentic sites.
View Case StudyDNA-PAINT provides easy localization-based super-resolution with nanorulers from GATTAquant GmbH.
View Case StudyDownload our EV Application Note explaining how researchers can size, track and characterize extracellular vesicles in solution or in live cells.
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