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12 of 363 results

biorxiv, April 2025

Single-vesicle tracking of α-synuclein oligomers reveals pore formation by a three-stage model modulated by charge, curvature, lipids and ligands

Bo Volf Brøchner, Xialin Zhang, Janni Nielsen, Jørgen Kjems, Daniel E. Otzen, Mette Galsgaard Malle

Tags
  • Signaling
  • Single-Particle Tracking

biorxiv, April 2025

Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

Roya Pournejati, Jessica M. Huang, Michael Ma, Claudia M. Moreno, Oscar Vivas

Tags
  • Signaling
  • dSTORM

biorxiv, April 2025

Nanoscale domains govern local diffusion and aging within FUS condensates

Guoming Gao, Emily R. Sumrall, Nils G. Walter

Tags
  • Signaling
  • HILO
  • Single-Particle Tracking

biorxiv, March 2025

Single-molecule validation and optimized protocols for the use of secondary nanobodies in multiplexed immunoassays

Rebecca S. Saleeb, Judi O’Shaughnessy, Ryan Ferguson, Candace T. Adams, Mathew H. Horrocks

Tags
  • dSTORM

biorxiv, March 2025

Control of physical and biochemical parameters influencing exogeneous cargo protein association to extracellular vesicles using lipid anchors enables high loading and effective intracellular delivery

Antonin Marquant, Jade Berthelot, Claudia Bich, Zeineb Ibn Elfekih, Laurianne Simon, Baptiste Robin, Joël Chopineau, David Tianpei Wang, Samuel Jay Emerson, Aijun Wang, Clément Benedetti, Simon Langlois, Laurence Guglielmi, Pierre Martineau, Anne Aubert-Pouëssel, Marie Morille

Tags
  • Extracellular vesicles
  • dSTORM

JCI Insight, March 2025

A toxic gain of function variant in MAPK8IP3 provides novel insights into JIP3 cellular roles

Wei Zhang, Swapnil Mittal, Ria Thomas, Anahid Foroughishafiei, Ricardo Nunes Bastos, Wendy K. Chung, Konstantina Skourti-Stathaki, Stanley T. Crooke

Tags
  • Signaling
  • dSTORM

Cell reports medicine, March 2025

Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease

Shijun Yan, Wenjing Zhang, Xinying Li, Suman Dutta, Andrew R. Castle, Yiming Liu, Anis Sahoo, Chor Lai Lam, Nicholas J.F. Gatford, Michele T. Hu, Chen-zhong Li, Cheng Jiang, Bowen Shu, George K. Tofaris

Tags
  • Extracellular vesicles
  • dSTORM

biorxiv, March 2025

STI1 domain dynamically engages transient helices in disordered regions to drive self-association and phase separation of yeast ubiquilin Dsk2

Nirbhik Acharya, Emily Daniel, Thuy P. Dao, Erin Mulvey, Daniel Kraut, Jeroen Roelofs, Carlos A. Castañeda

Tags
  • Live Imaging

biorxiv, March 2025

A central, shared role for disulfide bonds in Bacteroidota protein transport and gliding motility

Xiaolong Liu, Marieta Avramova, Justin C. Deme, Rachel L. Jones, Camilla A.K. Lundgren, Susan M. Lea, Ben C. Berks

Tags
  • Bacteria
  • Single-Particle Tracking

Colloids and Surfaces B: Biointerfaces,, March 2025

Investigating strategies for creating cross-linked amyloid fibril networks through branching of amyloid growth

William P. Olsen, Anne-Kathrine K. Larsen, Jakob L. Christensen, Mette G. Malle, Daniel E. Otzen,

Tags
  • TIRF

ACS nano, March 2025

Extracellular Vesicles Carrying Tenascin-C are Clinical Biomarkers and Improve Tumor-Derived DNA Analysis in Glioblastoma Patients

Amanda Salviano-Silva, Kathrin Wollmann, Santra Brenna, Rudolph Reimer, Julia E. Neumann, Matthias Dottermusch, Laura Woythe, Cecile L. Maire, Berta Puig, Ulrich Schüller, Meike J. Saul, Manfred Westphal, Richard Drexler, Lasse Dührsen, Jens Gempt, Dieter H. Heiland, Katrin Lamszus, Franz L. Ricklefs

Tags
  • Extracellular vesicles
  • dSTORM

Communications Biology, February 2025

Ribosome phenotypes for rapid classification of antibiotic-susceptible and resistant strains of Escherichia coli

Alison Farrar, Piers Turner, Hafez El Sayyed, Conor Feehily, Stelios Chatzimichail, Sammi Ta, Derrick Crook, Monique Andersson, Sarah Oakley, Lucinda Barrett, Christoffer Nellåker, Nicole Stoesser & Achillefs Kapanidis

Tags
  • Bacteria
  • Widefield