Single-particle tracking (SPT) in live cells allows us to measure the motion and changes in behavior of fluorescently-labeled particles, e.g. upon entering the cell, entering the nucleus or during viral egress (by lysis, exocytosis or budding through the plasma membrane).
The Nanoimager enables researchers to learn more about where particles are assembled, accumulate, transiently bind or move to. Additionally, it allows simultaneous dual color imaging, to easily follow two fluorophore species at the same time. It also has a Z-lock that facilitates imaging on a specific focal plane, as well as whole body heating and microfluidics support.
To precisely measure the effects on the cell of external stimuli, such as the environmental cues, growth conditions, mutations in the genome or exposure to drugs, our dedicated NimOS software offers a range of tools for quantitative data analysis. Information about particle size, number and diffusion coefficients can be instantly visualized, plotted and saved as a file compatible with other standard data analysis platforms.