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Communications Biology, March 2022

Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering

Franziska Heckel, Anna H. Turaj, Hayden Fisher, H. T. Claude Chan, Michael J. E. Marshall, Osman Dadas, Christine A. Penfold, Tatyana Inzhelevskaya, C. Ian Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen A. Beers, Mark S. Cragg & Sean H. Lim

Tags
  • Immuno-oncology

Actin Cytoskeleton in Cancer Progression and Metastasis–Part C, May 2021

Actin dynamics during tumor cell dissemination

Mondal, Chandrani, Julie S. Di Martino, and Jose Javier Bravo-Cordero.

Tags
  • Immuno-oncology
  • dSTORM

Nature Communications, June 2021

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition

Yunmin Jung, Lai Wen, Amnon Altman & Klaus Ley

Tags
  • Immuno-oncology
  • dSTORM

Communications Biology, June 2021

TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity

Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H. T. Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Martin J. Glennie & Mark S. Cragg

Tags
  • Immuno-oncology
  • dSTORM

Life Science Alliance, June 2021

Specific N-cadherin–dependent pathways drive human breast cancer dormancy in bone marrow

Garima Sinha, Alejandra I Ferrer, Seda Ayer, Markos H El-Far, Sri Harika Pamarthi, Yahaira Naaldijk, Pradeep Barak, Oleta A Sandiford, Bernadette M Bibber, Ghassan Yehia, Steven J Greco, Jie-Gen Jiang, Margarette Bryan, Rakesh Kumar, Nicholas M Ponzio, Jean-Pierre Etchegaray, Pranela Rameshwar

Tags
  • Immuno-oncology
  • dSTORM

Pharmaceutics, January 2021

Coincubation as miR-Loading Strategy to Improve the Anti-Tumor Effect of Stem Cell-Derived EVs

Alessia Brossa, Marta Tapparo, Valentina Fonsato, Elli Papadimitriou, Michela Delena, Giovanni Camussi and Benedetta Bussolati

Tags
  • Extracellular vesicles
  • Immuno-oncology
  • dSTORM
  • TIRF/HILO

The Journal of Immunology, May 2020

Using super-resolution microscopy to detect and resolve the distribution of biomarkers that are relevant in a range of immuno-oncology studies

Sheila Burns and Michael Senior

Tags
  • Immuno-oncology
  • dSTORM
  • Live imaging
  • Single-particle tracking

bioRxiv, May 2020

CD45 pre-exclusion from the tips of microvilli establishes a phosphatase-free zone for early TCR triggering

Yunmin Jung, Lai Wen, Amnon Altman, Klaus Ley

Tags
  • Immuno-oncology
  • dSTORM

Nature, January 2020

B cells and tertiary lymphoid structures promote immunotherapy response

Beth A. Helmink, Sangeetha M. Reddy, Jianjun Gao, Shaojun Zhang, Rafet Basar, Rohit Thakur, Keren Yizhak, Moshe Sade-Feldman, Jorge Blando, Guangchun Han, Vancheswaran Gopalakrishnan, Yuanxin Xi, Hao Zhao, Rodabe N. Amaria, Hussein A. Tawbi, Alex P. Cogdill, Wenbin Liu, Valerie S. LeBleu, Fernanda G. Kugeratski, Sapna Patel, Michael A. Davies, Patrick Hwu, Jeffrey E. Lee, Jeffrey E. Gershenwald, Anthony Lucci, Reetakshi Arora, Scott Woodman, Emily Z. Keung, Pierre-Olivier Gaudreau, Alexandre Reuben, Christine N. Spencer, Elizabeth M. Burton, Lauren E. Haydu, Alexander J. Lazar, Roberta Zapassodi, Courtney W. Hudgens, Deborah A. Ledesma, SuFey Ong, Michael Bailey, Sarah Warren, Disha Rao, Oscar Krijgsman, Elisa A. Rozeman, Daniel Peeper, Christian U. Blank, Ton N. Schumacher, Lisa H. Butterfield, Monika A. Zelazowska, Kevin M. McBride, Raghu Kalluri, James Allison, Florent Petitprez, Wolf Herman Fridman, Catherine Sautès-Fridman, Nir Hacohen, Katayoun Rezvani, Padmanee Sharma, Michael T. Tetzlaff, Linghua Wang & Jennifer A. Wargo

Tags
  • Extracellular vesicles
  • Immuno-oncology