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Nature Biomedical Engineering , June 2023

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

David P. Schrijver, Rutger J. Röring, Jeroen Deckers, Anne de Dreu, Yohana C. Toner, Geoffrey Prevot, Bram Priem, Jazz Munitz, Eveline G. Nugraha, Yuri van Elsas, Anthony Azzun, Tom Anbergen, Laszlo A. Groh, Anouk M. D. Becker, Carlos Pérez-Medina, Roderick S. Oosterwijk, Boris Novakovic, Simone J. C. F. M. Moorlag, Aron Jansen, Peter Pickkers, Matthijs Kox, Thijs J. Beldman, Ewelina Kluza, Mandy M. T. van Leent, …Willem J. M. Mulder

Tags
  • Immuno-oncology
  • dSTORM

Beginners guide to clustering on localization data

  • Immuno-oncology
  • dSTORM
  • SMLM
Tips & Tricks

Nature, February 2023

Reducing affinity as a strategy to boost immunomodulatory antibody agonism

Xiaojie Yu, Christian M. Orr, H. T. Claude Chan, Sonya James, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Jonathan W. Essex, Ivo Tews, Martin J. Glennie & Mark S. Cragg

Tags
  • Immuno-oncology
  • dSTORM

Webinar "Tips & Tricks - Using localization data clustering effectively"

  • Cell phenotyping
  • Immuno-oncology
  • Nanotechnology
  • dSTORM
Tips & Tricks

Webinar "Imaging beyond limits - Revealing immunology at the nanoscale with super-resolution microscopy"

  • Immuno-oncology
Webinars

Nature Communications, September 2022

Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation

Jennifer L. Johnson, Elsa Meneses-Salas, Mahalakshmi Ramadass, Jlenia Monfregola, Farhana Rahman, Raquel Carvalho Gontijo, William B. Kiosses, Kersi Pestonjamasp, Dale Allen, Jinzhong Zhang, Douglas G. Osborne, Yanfang Peipei Zhu, Nathan Wineinger, Kasra Askari, Danni Chen, Juan Yu, Scott C. Henderson, Catherine C. Hedrick, Matilde Valeria Ursini, Sergio Grinstein, Daniel D. Billadeau & Sergio D. Catz

Tags
  • Immuno-oncology

Cellular and Molecular Life Sciences , August 2022

Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells

Nicole Koller, Philipp Höllthaler, Martina Barends, Marius Döring, Christoph Spahn, Verónica Durán, Bibiana Costa, Jennifer Becker, Mike Heilemann, Ulrich Kalinke & Robert Tampé

Tags
  • Immuno-oncology
  • Single-Particle Tracking

Nature Communications, July 2022

Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors

Marcin Wegrecki, Tonatiuh A. Ocampo, Sachith D. Gunasinghe, Anouk von Borstel, Shin Yi Tin, Josephine F. Reijneveld, Thinh-Phat Cao, Benjamin S. Gully, Jérôme Le Nours, D. Branch Moody, Ildiko Van Rhijn & Jamie Rossjohn

Tags
  • Immuno-oncology
  • dSTORM

Communications Biology, March 2022

Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering

Franziska Heckel, Anna H. Turaj, Hayden Fisher, H. T. Claude Chan, Michael J. E. Marshall, Osman Dadas, Christine A. Penfold, Tatyana Inzhelevskaya, C. Ian Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen A. Beers, Mark S. Cragg & Sean H. Lim

Tags
  • Immuno-oncology
  • Confocal

Actin Cytoskeleton in Cancer Progression and Metastasis–Part C, May 2021

Actin dynamics during tumor cell dissemination

Mondal, Chandrani, Julie S. Di Martino, and Jose Javier Bravo-Cordero.

Tags
  • Immuno-oncology
  • dSTORM

Nature Communications, June 2021

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition

Yunmin Jung, Lai Wen, Amnon Altman & Klaus Ley

Tags
  • Immuno-oncology
  • dSTORM

Communications Biology, June 2021

TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity

Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H. T. Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Martin J. Glennie & Mark S. Cragg

Tags
  • Immuno-oncology
  • dSTORM