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iScience, October 2020

Specific N-Cadherin-Dependent Pathways Drive Human Breast Cancer Dormancy in Bone Marrow

Garima Sinha, Alejandra Ferrer, Seda Ayer, Markos El-Far, Sri Harika Parmarthi, Yahaira Naaldijk, Pradeep Barak, Oleta Sandiford, Bernadette Bibber, Ghassan Yehia, Steven Greco, Jie-Gen Jiang, Margarette Bryan, Rakesh Kumar, Nicholas Ponzio, Jean-Pierre Etchegaray, Pranela Rameshwar

Tags
  • Cell phenotyping
  • Widefield

Science Advances , December 2020

Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors

Antony Hsieh, Jason R. Pitarresi, Jonathan Lerner et al.

Tags
  • Cell phenotyping
  • Live imaging
  • Single-particle tracking

Biorxiv, September 2020

Decreased calmodulin recruitment triggers PMCA4 dysfunction and pancreatic injury in cystic fibrosis

Tamara Madácsy, Árpad Varga, Noémi Papp, Barnabás Deák, Bálint Tél, Petra Pallagi, Viktória Szabó, Júlia Fanczal, Zoltan Rakonczay Jr., Zsolt Rázga, Meike Hohwieler, Alexander Kleger, Mike Gray, Péter Hegyi, József Maléth

Tags
  • Cell phenotyping
  • dSTORM

biorxiv, April 2021

Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions

Anna Bodzęta, Florian Berger, Harold D. MacGillavry

Tags
  • Cell phenotyping
  • Neuroscience
  • PAINT
  • Single-particle tracking

PNAS, May 2021

Tau forms oligomeric complexes on microtubules that are distinct from pathological oligomers in disease

M. T. Gyparaki, A. Arab, E. M. Sorokina, A. N. Santiago-Ruiz, C. H. Bohrer, J. Xiao, M. Lakadamyali,

Tags
  • Cell phenotyping
  • Neuroscience
  • dSTORM
  • SMLM
  • Widefield

Examining T Cell Activation and Inhibition at the Nanoscale Using dSTORM

  • Cell phenotyping
  • Immuno-oncology
  • dSTORM
Application note

Biosafety Cabinets

Until recently, due to their size and design, the majority of super-resolution microscopes have not been able to support research in enclosed, ventilated biosafety cabinets. But things are changing.

  • Cell phenotyping
  • Immuno-oncology

Protein Complex Assembly

Intensity measurements, super-resolution and multi-color labeling for characterizing protein complexes and their assembly.

  • smFRET
  • Cell phenotyping