<p><strong>Interested in LNP research?</strong> Discover the advantages of SMLM for lipid nanoparticles! <span style="text-decoration: underline;">learn more</span></p>

Interested in LNP research? Discover the advantages of SMLM for lipid nanoparticles! learn more

Science Advances , December 2020

Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors

Antony Hsieh, Jason R. Pitarresi, Jonathan Lerner et al.

Tags
  • Cell phenotyping
  • Brightfield
  • HILO
  • Live Imaging
  • Single-Particle Tracking

Investigating nuclear pore complexes at the single-molecule level

  • Cell phenotyping
  • dSTORM
  • TIRF
Application Notes

Biorxiv, September 2020

Decreased calmodulin recruitment triggers PMCA4 dysfunction and pancreatic injury in cystic fibrosis

Tamara Madácsy, Árpad Varga, Noémi Papp, Barnabás Deák, Bálint Tél, Petra Pallagi, Viktória Szabó, Júlia Fanczal, Zoltan Rakonczay Jr., Zsolt Rázga, Meike Hohwieler, Alexander Kleger, Mike Gray, Péter Hegyi, József Maléth

Tags
  • Cell phenotyping
  • dSTORM

biorxiv, April 2021

Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions

Anna Bodzęta, Florian Berger, Harold D. MacGillavry

Tags
  • Cell phenotyping
  • Neuroscience
  • PAINT
  • Single-Particle Tracking

PNAS, May 2021

Tau forms oligomeric complexes on microtubules that are distinct from pathological oligomers in disease

M. T. Gyparaki, A. Arab, E. M. Sorokina, A. N. Santiago-Ruiz, C. H. Bohrer, J. Xiao, M. Lakadamyali,

Tags
  • Cell phenotyping
  • Neuroscience
  • dSTORM
  • SMLM
  • Widefield

Capturing organelle contact sites assembly to unveil disease onset in live cells

Learn how the Nanoimager allows real-time visualization and quantification of cellular processes at a single-molecule level, in live cells.

  • Cell phenotyping
  • Single-Particle Tracking
Application Notes

Biosafety Cabinets

Until recently, due to their size and design, the majority of super-resolution microscopes have not been able to support research in enclosed, ventilated biosafety cabinets. But things are changing.

  • Bacteria
  • Cell phenotyping
  • Immuno-oncology

Protein Complex Assembly

Intensity measurements, super-resolution and multi-color labeling for characterizing protein complexes and their assembly.

  • smFRET
  • Bacteria
  • Cell phenotyping