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12 of 323 results

BiorXiv, June 2023

The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

Marisa Luisa Martin-Fernandez, Sumanth Iyer, Sarah R Needham, Ioannis Galgadas, Benjamin M Davis, Selene K Roberts, Rico CH Man, Laura C Zanetti-Domingues, Dave T Clarke, Gilbert O Fruhwirth, Peter J Parker, D J Rolfe, Francesco L Gervasio

Tags
  • Immuno-oncology
  • dSTORM

Nature Biomedical Engineering , June 2023

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

David P. Schrijver, Rutger J. Röring, Jeroen Deckers, Anne de Dreu, Yohana C. Toner, Geoffrey Prevot, Bram Priem, Jazz Munitz, Eveline G. Nugraha, Yuri van Elsas, Anthony Azzun, Tom Anbergen, Laszlo A. Groh, Anouk M. D. Becker, Carlos Pérez-Medina, Roderick S. Oosterwijk, Boris Novakovic, Simone J. C. F. M. Moorlag, Aron Jansen, Peter Pickkers, Matthijs Kox, Thijs J. Beldman, Ewelina Kluza, Mandy M. T. van Leent, …Willem J. M. Mulder

Tags
  • Immuno-oncology
  • dSTORM

ACS Nano, June 2023

Mapping Antibody Domain Exposure on Nanoparticle Surfaces Using DNA-PAINT

Marrit M. E. Tholen Marrit M. E. Tholen Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, 5612 AZ Eindhoven, The Netherlands More by Marrit M. E. Tholen Orcidhttps://orcid.org/0000-0002-4066-6064 , Bas J. H. M. Rosier, Robin T. Vermathen, Céline A. N. Sewnath, Cornelis Storm, Laura Woythe, Cristina Izquierdo-Lozano, Roger Riera, Marjolein van Egmond, Maarten Merkx, and Lorenzo Albertazzi

Tags
  • Nanotechnology
  • PAINT

Journal of extracellular vesicles , June 2023

Large-scale heparin-based bind-and-elute chromatography identifies two biologically distinct populations of extracellular vesicles

Yijun Zhou PhD, Runjie Yuan, Allaura S. Cone PhD, Kyle W. Shifflett, Gabriel F. Arias, Alice Peng, Meredith G. Chambers, Ryan P. McNamara PhD, Smaranda Willcox, Justin T. Landis, Yue Pan PhD, Jack Griffith PhD, Dirk P. Dittmer PhD

Tags
  • Extracellular vesicles
  • dSTORM

J Cell Biol , May 2023

Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1

Laura Hakanpää, Amr Abouelezz, An-Sofie Lenaerts, Seyda Culfa, Michael Algie, Jenny Bärlund, Pekka Katajisto, Harvey McMahon, Leonardo Almeida-Souza;

Tags
  • Live Imaging
  • TIRF

Methods in Molecular Biology, May 2023

Quantitative Analysis of PcG-Associated Condensates by Stochastic Optical Reconstruction Microscopy (STORM)

Silvia Scalisi, Ali Ahmad, Sarah D’Annunzio, David Rousseau & Alessio Zippo

Tags
  • Signaling
  • dSTORM

Res Pract Thromb Haemost., May 2023

Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability

Joanne L. Mitchell, Gemma Little, Alexander P. Bye, Renato S. Gaspar, Amanda J. Unsworth, Neline Kriek, Tanya Sage, Alexander Stainer, Ibidayo Sangowawa, Gael B. Morrow, Ricardo N. Bastos, Susan Shapiro, Michael J.R. Desborough, Nicola Curry, Jonathan M. Gibbins, Claire S. Whyte, Nicola J. Mutch, Christopher I. Jones,

Tags
  • dSTORM

Journal of Controlled Release, April 2023

Surface display of functional moieties on extracellular vesicles using lipid anchors

Wenyi Zheng, Melanie Schürz, Rim Jawad Wiklander, Oskar Gustafsson, Dhanu Gupta, Radka Slovak, Andrei Traista, Arianna Coluzzi, Samantha Roudi, Antonella Barone, Daria Farcas, Eleni Kyriakopoulou, Valentina Galli, Heena Sharma, Nicole Meisner-Kober, Malgorzata Honcharenko, Samir E.L. Andaloussi,

Tags
  • Extracellular vesicles
  • dSTORM

BiorXiv, April 2023

RAD52 prevents accumulation of Polα-dependent replication gaps at perturbed replication forks in human cells

Ludovica Di Biagi, Eva Malacaria, Francesca Antonella Aiello, Pasquale Valenzisi, Giorgia Marozzi, Annapaola Franchitto, Pietro Pichierri

Tags
  • dSTORM

IMMUNOLOGY AND INFLAMMATION, April 2023

Phosphatidylserine-positive extracellular vesicles boost effector CD8+ T cell responses during viral infection

Lisa Rauscha,1 , Lavinia Flaskampa, Ashretha Ashokkumara, Anne Trefzera, Christine Rieda, Veit R. Buchholzb , Reinhard Obsta , Tobias Straubc, Thomas Brockera, and Jan Kranich

Tags
  • dSTORM

medRxiv , March 2023

Synaptic oligomeric tau in Alzheimer’s disease – a potential culprit in the spread of tau pathology through the brain

Martí Colom-Cadena, Caitlin Davies, Sònia Sirisi, Ji-Eun Lee, Elizabeth Simzer, Makis Tzioras, Marta Querol-Vilaseca, Érika Sánchez-Aced, Ya Yin Chang, Kris Holt, Robert McGeachan, Jamie Rose, Jane Tulloch, Lewis Wilkins, Colin Smith, Teodora Andrian, Olivia Belbin, Sílvia Pujals, Mathew H. Horrocks, Alberto Lleó, Tara Spires-Jones

Tags
  • Neuroscience
  • PAINT

Journal of Extracellular Biology, March 2023

Comparison of different methods for isolating CD8+ T lymphocyte-derived extracellular vesicles and supramolecular attack particles

Ashwin K. Jainarayanan, Jesusa Capera, Pablo F. Céspedes, Mariana Conceição, Mirudula Elanchezhian, Tom Thomas, Scott Bonner, Salvatore Valvo, Elke Kurz, Ranjeet Singh Mahla, Georgina Berridge, Svenja Hester, Roman Fischer, Lynn B. Dustin, Matthew J. A. Wood, Michael L. Dusti

Tags
  • Extracellular vesicles
  • dSTORM
  • TIRF