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Nature Biomedical Engineering, March 2024

PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes

Ruiyang Pang, Weihao Sun, Yingyun Yang, Dahan Wen, Feng Lin, Dingding Wang, Kailong Li, Ning Zhang, Junbo Liang, Chunyang Xiong & Yuying Liu

Tags
  • Immuno-oncology
  • dSTORM

BiorXiv, April 2024

Elucidation of the molecular mechanism of the breakage-fusion-bridge (BFB) cycle using a CRISPR-dCas9 cellular model

Manrose Singh, Kaitlin Raseley, Alexis M. Perez, Danny MacKenzie, Settapong T Kosiyatrakul, Sanket Desai, Noelle Batista, Navjot Guru, Katherine K. Loomba, Heba Z. Abid, Yilin Wang, Lars Udo-Bellner, Randy F. Stout, Carl L. Schildkraut, Ming Xiao, Dong Zhang

Tags
  • Nanotechnology
  • dSTORM

Extracell Vesicles Circ Nucleic Acids , March 2024

Non-invasive detection of orthotopic human lung tumors by microRNA expression profiling of mouse exhaled breath condensates and exhaled extracellular vesicles

Mitchell MI, Ben-Dov IZ, Liu C, Wang T, Hazan RB, Bauer TL, Zakrzewski J, Donnelly K, Chow K, Ma J, Loudig O.

Tags
  • Extracellular vesicles
  • dSTORM

BiorXiv, April 2024

Thrombospondins 1 and 4 undergo coordinated transport to multicore cytotoxic granules to regulate SMAP biogenesis and function in CTL-mediated cytotoxicity

Chiara Cassioli, Nagaja Capitani, Claire C. Staton, Claudia Schirra, Francesca Finetti, Anna Onnis, Nadia Alawar, Szu-Min Tu, Ludovica Lopresti, Vanessa Tatangelo, Carmela Tangredi, Salvatore Valvo, Hsin-Fang Chang, Annachiara Miccoli, Ewaldus B. Compeer, Jemma Nicholls, Bruce Blazar, Giuseppe Marotta, Matthew J. A. Wood, Livio Trentin, Laura Patrussi, Michael L. Dustin, Ute Becherer, Cosima T. Baldari

Tags
  • Immuno-oncology
  • dSTORM

Journal of Extracellular Vesicles, May 2024

Neonatal enteroids absorb extracellular vesicles from human milk-fed infant digestive fluid

Yung C, Zhang Y, Kuhn M, Armstrong RJ, Olyaei A, Aloia M, Scottoline B, Andres SF

Tags
  • Extracellular vesicles
  • dSTORM

Cell Rep, May 2024

Dissecting gene activation and chromatin remodeling dynamics in single human cells undergoing reprogramming

Martinez-Sarmiento JA, Cosma MP, Lakadamyali M.

Tags
  • Signaling
  • dSTORM
  • smFISH

Nature Communications, March 2024

Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2

Zhenzhen Wang, Shiqi Hu, Kristen D. Popowski, Shuo Liu, Dashuai Zhu, Xuan Mei, Junlang Li, Yilan Hu, Phuong-Uyen C. Dinh, Xiaojie Wang & Ke Cheng

Tags
  • Extracellular vesicles
  • Virology
  • dSTORM

EMBO Mol Med, March 2024

Generalizable anchor aptamer strategy for loading nucleic acid therapeutics on exosomes

Han G, Zhang Y, Zhong L, Wang B, Qiu S, Song J, Lin C, Zou F, Wu J, Yu H, Liang C, Wen K, Seow Y, Yin H.

Tags
  • Extracellular vesicles
  • dSTORM

Journal of Extracellular Biology, February 2024

Profile of matrix-entrapped extracellular vesicles of microenvironmental and infiltrating cell origin in decellularized colorectal cancer and adjacent mucosa

Sarah Tassinari, Edoardo D'Angelo, Federico Caicci, Cristina Grange, Jacopo Burrello, Matteo Fassan, Alessia Brossa, Riccardo Quoc Bao, Gaya Spolverato, Marco Agostini, Federica Collino, Benedetta Bussolati

Tags
  • Extracellular vesicles
  • dSTORM

BiorXiv, March 2024

Scalable Isolation of Surface-Engineered Extracellular Vesicles and Separation of Free Proteins via Tangential Flow Filtration and Size Exclusion Chromatography (TFF-SEC)

Yuki Kawai-Harada, Vasudha Nimmagadda, Masako Harada

Tags
  • Extracellular vesicles
  • dSTORM