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Nature , June 2022

Peptidoglycan maturation controls outer membrane protein assembly

Gideon Mamou, Federico Corona, Ruth Cohen-Khait, Dawei Sun, Pooja Sridhar, Timothy J. Knowles, Colin Kleanthous, Waldemar Vollmer

Tags
  • Bacteria
  • Live Imaging
  • TIRF

ACS Nano, November 2021

Antibiotic-Loaded Polymersomes for Clearance of Intracellular Burkholderia thailandensis

Eleanor Porges, Dominic Jenner, Adam W. Taylor, James S. P. Harrison, Antonio De Grazia, Alethia R. Hailes, Kimberley M. Wright, Adam O. Whelan, Isobel H. Norville, Joann L. Prior, Sumeet Mahajan, Caroline A. Rowland, Tracey A. Newman, and Nicholas D. Evans

Tags
  • Bacteria

PNAS, November 2021

Phase separation in the outer membrane of Escherichia coli

Georgina Benn, Irina V. Mikheyeva, Patrick George Inns, Joel C. Forster, Nikola Ojkic, Christian Bortolini, Maxim G. Ryadnov, Colin Kleanthous, Thomas J. Silhavy, and Bart W. Hoogenboom

Tags
  • Bacteria

bioRxiv, April 2021

The association between Hfq and RNase E in long-term nitrogen starved Escherichia coli

Josh McQuail, Agamemnon J. Carpousis, Sivaramesh Wigneshweraraj

Tags
  • Bacteria
  • PALM
  • Single-Particle Tracking

bioRxiv preprint, January 2021

Spatiotemporal organization of BamA governs the pattern of outer membrane protein distribution in growing Escherichia coli cells

Gideon Mamou, Patrick G. Inns, Dawei Sun, Renata Kaminska, Nicholas G. Housden, Ruth Cohen-Khait, Helen Miller, Kelly M. Storek, Steven T. Rutherford, Jian Payandeh & Colin Kleanthous

Tags
  • Bacteria
  • Brightfield
  • HILO
  • TIRF

Exploring adaptive responses in bacteria using the Nanoimager

  • Bacteria
  • PALM
  • Single-Particle Tracking
Application Notes

Infection and Immunity, August 2020

Genomic Profiling Reveals Distinct Routes To Complement Resistance in Klebsiella pneumoniae

Francesca L. Short, Gianna Di Sario, Nathalie T. Reichmann, Colin Kleanthous, Julian Parkhill, Peter W. Taylor

Tags
  • Bacteria
  • HILO

Characterizing bacterial infection in epithelial cells at a single-molecule level

Learn how the Nanoimager enables visualization and quantification of bacterial infection and host-pathogen interactions at a single-molecule level.

  • Bacteria
  • dSTORM
Application Notes

Developing new antibiotics: from target identification to mechanism validation

Learn how the Nanoimager provides a multiplex solution for novel antibiotic development.

  • Bacteria
  • PALM
  • Single-Particle Tracking
Application Notes

Journal of Biological Chemistry, May 2020

Bifurcated binding of the OmpF receptor underpins import of the bacteriocin colicin N into Escherichia coli

Katarina Bartoš Jansen, Patrick George Inns, Nicholas George Housden, Jonathan T S Hopper , Renata Kaminska, Sejeong Lee, Carol V Robinson, Hagan Bayley, Colin Kleanthous

Tags
  • Bacteria
  • Widefield