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Introducing Aplo Scope: A new era in super-resolution imaging! learn more >

BiorXiv, June 2023

The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

Marisa Luisa Martin-Fernandez, Sumanth Iyer, Sarah R Needham, Ioannis Galgadas, Benjamin M Davis, Selene K Roberts, Rico CH Man, Laura C Zanetti-Domingues, Dave T Clarke, Gilbert O Fruhwirth, Peter J Parker, D J Rolfe, Francesco L Gervasio

Tags
  • Immuno-oncology
  • dSTORM

Nature Biomedical Engineering , June 2023

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

David P. Schrijver, Rutger J. Röring, Jeroen Deckers, Anne de Dreu, Yohana C. Toner, Geoffrey Prevot, Bram Priem, Jazz Munitz, Eveline G. Nugraha, Yuri van Elsas, Anthony Azzun, Tom Anbergen, Laszlo A. Groh, Anouk M. D. Becker, Carlos Pérez-Medina, Roderick S. Oosterwijk, Boris Novakovic, Simone J. C. F. M. Moorlag, Aron Jansen, Peter Pickkers, Matthijs Kox, Thijs J. Beldman, Ewelina Kluza, Mandy M. T. van Leent, …Willem J. M. Mulder

Tags
  • Immuno-oncology
  • dSTORM

Methods in Molecular Biology, May 2023

Quantitative Analysis of PcG-Associated Condensates by Stochastic Optical Reconstruction Microscopy (STORM)

Silvia Scalisi, Ali Ahmad, Sarah D’Annunzio, David Rousseau & Alessio Zippo

Tags
  • Signaling
  • dSTORM

IMMUNOLOGY AND INFLAMMATION, April 2023

Phosphatidylserine-positive extracellular vesicles boost effector CD8+ T cell responses during viral infection

Lisa Rauscha,1 , Lavinia Flaskampa, Ashretha Ashokkumara, Anne Trefzera, Christine Rieda, Veit R. Buchholzb , Reinhard Obsta , Tobias Straubc, Thomas Brockera, and Jan Kranich

Tags
  • dSTORM

Nature, February 2023

Reducing affinity as a strategy to boost immunomodulatory antibody agonism

Xiaojie Yu, Christian M. Orr, H. T. Claude Chan, Sonya James, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Jonathan W. Essex, Ivo Tews, Martin J. Glennie & Mark S. Cragg

Tags
  • Immuno-oncology
  • dSTORM

Journal of Extracellular Biology, March 2023

Comparison of different methods for isolating CD8+ T lymphocyte-derived extracellular vesicles and supramolecular attack particles

Ashwin K. Jainarayanan, Jesusa Capera, Pablo F. Céspedes, Mariana Conceição, Mirudula Elanchezhian, Tom Thomas, Scott Bonner, Salvatore Valvo, Elke Kurz, Ranjeet Singh Mahla, Georgina Berridge, Svenja Hester, Roman Fischer, Lynn B. Dustin, Matthew J. A. Wood, Michael L. Dusti

Tags
  • Extracellular vesicles
  • dSTORM
  • TIRF