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Communications Biology, February 2025

Ribosome phenotypes for rapid classification of antibiotic-susceptible and resistant strains of Escherichia coli

Alison Farrar, Piers Turner, Hafez El Sayyed, Conor Feehily, Stelios Chatzimichail, Sammi Ta, Derrick Crook, Monique Andersson, Sarah Oakley, Lucinda Barrett, Christoffer Nellåker, Nicole Stoesser & Achillefs Kapanidis

Tags
  • Bacteria
  • Widefield

Pharmaceuticals, December 2024

Kojic Acid Derivative as an Antimitotic Agent That Selectively Kills Tumour Cells

Pichiri, G.; Piludu, M.; Congiu, T.; Grandi, N.; Coni, P.; Piras, M.; Jaremko, M.; Lachowicz, J.I. Kojic

Tags
  • Immuno-oncology
  • Widefield

Nature Communications, September 2024

Controlled mechanochemical coupling of anti-junctions in DNA origami arrays

Fiona Cole, Martina Pfeiffer, Dongfang Wang, Tim Schröder, Yonggang Ke & Philip Tinnefeld

Tags
  • Nanotechnology
  • Widefield

Scientific reports, March 2024

Pathogenic mutations in UBQLN2 exhibit diverse aggregation propensity and neurotoxicity

Nathaniel Safren, Thuy P. Dao, Harihar Milaganur Mohan, Camellia Huang, Bryce Trotter, Carlos A. Castañeda, Henry Paulson, Sami Barmada & Lisa M. Sharkey

Tags
  • Widefield

BiorXiv, March 2024

Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate

Isabella M Valentino, Jeniffer G Llivicota-Guaman, Thuy P Dao, Erin O Mulvey, Andrew M Lehman, Sarasi K. K. Galagedera, Erica L Mallon, Carlos A Castañeda, Daniel A Kraut

Tags
  • Widefield

BiorXiv, February 2024

GLP1 receptor agonism ameliorates Parkinson’s disease through modulation of neuronal insulin signalling and glial suppression

Dilan Athauda, James R Evans, Laura Mahoney-Sanchez, Gurvir S Virdi, Patricia Lopez-Garcia, Anna Wernick, Aaron Wagen, Karishma D’Sa, Joanne Lachica, Stephanie Strohbuecker, Giulia Vecchi, Craig Leighton, Rebecca S. Saleeb, Judi O’Shaughnessy, Christina E. Toomey, Nirosen Vijiaratnam, Christine Girges, Yazhou Li, Maja Mustapic, Khalida Ismail, Melanie Davies, Dimitrios Kapogiannis, Minee L Choi, Mina Ryten, Mathew H. Horrocks, Nigel Greig, Thomas Foltynie, Sonia Gandhi

Tags
  • Widefield

BiorXiv, March 2024

Spatial targeting of the prostaglandin receptor EP2 to very early endosomes co-ordinates PGE2-mediated cAMP signaling in decidualizing human endometrium

Paul J. Brighton, Abigail R. Walker, Oliver Mann, Chow-Seng Kong, Emma S. Lucas, Pavle Vrljicak, Jan J. Brosens, Aylin C. Hanyaloglu

Tags
  • Signaling
  • Widefield

medrxiv, December 2023

Infection Inspection: Using the power of citizen science to help with image-based prediction of antibiotic resistance in Escherichia coli

Alison Farrar, Conor Feehily, Piers Turner, Aleksander Zagajewski, Stelios Chatzimichail, Derrick Crook, Monique Andersson, Sarah Oakley, Lucinda Barrett, Hafez El Sayyed, Philip W. Fowler, Christoffer Nellåker, Achillefs N. Kapanidis, Nicole Stoesser

Tags
  • Bacteria
  • Widefield