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biorxiv, March 2025

Control of physical and biochemical parameters influencing exogeneous cargo protein association to extracellular vesicles using lipid anchors enables high loading and effective intracellular delivery

Antonin Marquant, Jade Berthelot, Claudia Bich, Zeineb Ibn Elfekih, Laurianne Simon, Baptiste Robin, Joël Chopineau, David Tianpei Wang, Samuel Jay Emerson, Aijun Wang, Clément Benedetti, Simon Langlois, Laurence Guglielmi, Pierre Martineau, Anne Aubert-Pouëssel, Marie Morille

Tags
  • Extracellular vesicles
  • dSTORM

JCI Insight, March 2025

A toxic gain of function variant in MAPK8IP3 provides novel insights into JIP3 cellular roles

Wei Zhang, Swapnil Mittal, Ria Thomas, Anahid Foroughishafiei, Ricardo Nunes Bastos, Wendy K. Chung, Konstantina Skourti-Stathaki, Stanley T. Crooke

Tags
  • Signaling
  • dSTORM

ACS nano, March 2025

Extracellular Vesicles Carrying Tenascin-C are Clinical Biomarkers and Improve Tumor-Derived DNA Analysis in Glioblastoma Patients

Amanda Salviano-Silva, Kathrin Wollmann, Santra Brenna, Rudolph Reimer, Julia E. Neumann, Matthias Dottermusch, Laura Woythe, Cecile L. Maire, Berta Puig, Ulrich Schüller, Meike J. Saul, Manfred Westphal, Richard Drexler, Lasse Dührsen, Jens Gempt, Dieter H. Heiland, Katrin Lamszus, Franz L. Ricklefs

Tags
  • Extracellular vesicles
  • dSTORM

biorxiv, March 2025

Single-molecule validation and optimized protocols for the use of secondary nanobodies in multiplexed immunoassays

Rebecca S. Saleeb, Judi O’Shaughnessy, Ryan Ferguson, Candace T. Adams, Mathew H. Horrocks

Tags
  • dSTORM

biorxiv, April 2025

Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

Roya Pournejati, Jessica M. Huang, Michael Ma, Claudia M. Moreno, Oscar Vivas

Tags
  • Signaling
  • dSTORM

Cell reports medicine, March 2025

Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease

Shijun Yan, Wenjing Zhang, Xinying Li, Suman Dutta, Andrew R. Castle, Yiming Liu, Anis Sahoo, Chor Lai Lam, Nicholas J.F. Gatford, Michele T. Hu, Chen-zhong Li, Cheng Jiang, Bowen Shu, George K. Tofaris

Tags
  • Extracellular vesicles
  • dSTORM

Science Advances, January 2025

Ultrasensitive detection of intact SARS-CoV-2 particlesin complex biofluids using microfluidic affinity capture

Rabe DC, Choudhury A, Lee D, Luciani EG, Ho UK, Clark AE, Glasgow JE, Veiga S, Michaud WA, Capen D, Flynn EA, Hartmann N, Garretson AF, Muzikansky A, Goldberg MB, Kwon DS, Yu X, Carlin AF, Theriault Y, Wells JA, Lennerz JK, Lai PS, Rabi SA, Hoang AN, Boland GM, Stott SL

Tags
  • Virology
  • dSTORM

Journal of Clinical Pathology, January 2025

Single-molecule localisation microscopy (SMLM) is feasible in human and animal formalin fixed paraffin embedded (FFPE) tissues in medical renal disease

Scarlet F. Brockmoeller, Hayley Slaney, Alistair Curd, Aurora Bono, James H. Felce, Deep Arora, Andrew Lewington, Andras G. Miklosi, Philip Quirke

Tags
  • Immuno-oncology
  • dSTORM