ONI Expands LNP Research Capabilities with Super-Resolution Characterization Service

FOR IMMEDIATE RELEASE

ONI Expands LNP Research Capabilities with Super-Resolution Characterization Service

SAN DIEGO, CA and OXFORD, UK, September 4, 2025 –

Oxford Nanoimaging (ONI), a global leader in super-resolution microscopy and single-particle analysis, today announced the launch of its LNP Sample Characterization Service, providing researchers with high-resolution insights into lipid nanoparticle (LNP) formulations.

This end-to-end service leverages ONI’s Aplo Scope and the LNP Profiler Kit with AutoLNP software to characterize LNP samples with single-molecule sensitivity. The service delivers quantitative insights into particle size, cargo loading, ligand positivity, stability, and aggregation, enabling scientists to make confident, data-driven decisions. Samples are run in triplicate, with fast turnaround times and cost-effective “Go/No-Go” quality control steps.

Service Offerings

• Small Batch (5–9 samples): Ideal for proof-of-concept studies, small batch testing, and initial LNP characterization. Turnaround: 1–2 weeks.
• Scale-Up (10+ samples): Optimized for method development, formulation comparison, and larger-scale characterization. Turnaround: 2–3 weeks.
• Tailored (10+ samples): For non-standard particle formulations, cell-based analysis, QC, or high-throughput screening. Turnaround: customized.

“We’re excited to announce the launch of ONI’s LNP characterisation service, offering super-resolution nanoparticle particle analysis to the entire LNP community,” says Dr. Ricardo Bastos, VP Strategy at ONI. “By combining automated, super-resolution imaging with single-particle & population level analysis, we provide scientists with unparalleled clarity on LNP heterogeneity and quality. We’re launching this service to help biopharma teams & academic researchers alike, accelerating R&D timelines, improving formulation decisions with confidence, and ultimately setting a new standard for how the industry approaches LNP design & development.”

The ONI Advantage
ONI’s service streamlines LNP analysis from sample preparation to imaging, visualization, and reporting. By providing standardized, high-quality data with quantified results, the service empowers scientists to explore LNP heterogeneity, optimize formulations, and accelerate R&D timelines with confidence.

The LNP Sample Characterization Service is now available to the scientific community.

???? Learn more or request a quote: https://oni.bio/lnp-sample-characterization/

About ONI 

ONI is a private, venture backed life sciences tools company transforming therapeutic discovery with accessible, high-performance super-resolution microscopy and funded by ARCH Venture Partners, Casdin Captial, Oxford Science Enterprises (OSE) and more. The company’s first product, the Nanoimager, introduced the world’s first desktop platform for single-molecule imaging, offering 20 nm resolution to study individual molecules in living cells, tissue, and nanoparticles. ONI’s latest innovation, the Aplo Scope, is a compact, end-to-end imaging platform that delivers unmatched clarity, precision, and speed. Designed to empower researchers, the Aplo Scope provides real-time insights into complex biological systems, enabling breakthroughs in drug delivery, biomarker discovery, and antibody therapeutics. For more information, visit oni.bio. Follow ONI @oniHQ and LinkedIn. 

For media inquiries, please contact:
Carolyn Hartmann
Director of Product Marketing, ONI
chartmann@oni.bio