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Scientific papers featuring ONI's Nanoimager

  • Ultraspecific analyte detection by direct kinetic fingerprinting of single molecules

    Chatterjee et al.

    Trends in Analytical Chemistry, February 2020

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  • Highly photostable fluorescent labeling of proteins in live cells using exchangeable coiled coils heterodimerization

    Perfilov et al.

    Cellular and Molecular Life Sciences, January 2020

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  • The formation and function of focus-like structures of Hfq in long-term nitrogen starved Escherichia coli

    McQuail et al.

    bioRxiv, January 2020

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  • Fluorophore photostability and saturation in the hotspot of DNA origami nanoantennas

    Grabenhorst et al.

    Methods and Applications in Fluorescence, January 2020

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  • B cells and tertiary lymphoid structures promote immunotherapy response

    Helmink et al.

    Nature, January 2020

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  • Extrusion of RNA from a DNA-Origami-Based Nanofactory

    Hahn et al.

    ACS Nano, January 2020

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  • Live-cell nanoscopy with spontaneous blinking of conventional green fluorescent proteins

    Gavrikov et al.

    Biochemical and Biophysical Research Communications, December 2019

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  • Confinement-Free Wide-Field Ratiometric Tracking of Single Fluorescent Molecules

    Gilboa et al.

    Biophysical Journal, December 2019

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  • Rapid functionalisation and detection of viruses via a novel Ca2+-mediated virus-DNA interaction

    Robb et al.

    Scientific Reports, November 2019

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  • Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque responses

    Oggero et al.

    bioRxiv, November 2019

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  • Lis1 regulates Phagocytosis by co-localising with actin in the Phagocytic cup

    Chhatre et al.

    bioRxiv, November 2019

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  • Pyocin S5 import into Pseudomonas aeruginosa reveals a generic mode of bacteriocin transport

    Behrens et al.

    bioRxiv, November 2019

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  • Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism

    Szczepaniak et al.

    bioRxiv, October 2019

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  • High-Throughput Detection and Manipulation of Single Nitrogen-Vacancy Center's Charge in Nanodiamonds

    Sow et al.

    arXiv, September 2019

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  • Actin‐Spectrin Scaffold Supports Open Fenestrae in Liver Sinusoidal Endothelial Cells

    Zapotoczny et al.

    Traffic, September 2019

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  • Mechanism of Enhanced MerTK-Dependent Macrophage Efferocytosis by Extracellular Vesicles

    de Couto et al.

    Arteriosclerosis, Thrombosis, and Vascular Biology, August 2019

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  • Single Fluorescent Peptide Nanodots

    Lapshina et al.

    ACS Photonics, June 2019

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  • Single Amino Acid Substitutions in Stickers, but Not Spacers, Substantially Alter UBQLN2 Phase Transitions and Dense Phase Material Properties

    Yang et al.

    The Journal of Physical Chemistry B, March 2019

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  • Effective Visualization and Easy Tracking of Extracellular Vesicles in Glioma Cells

    Mondal et al.

    Biological Procedures Online, March 2019

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  • A Bayesian Nonparametric Approach to Single Molecule Förster Resonance Energy Transfer

    Sgouralis et al.

    Journal of Physical Chemistry B, January 2019

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  • Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome-autophagosome fusion

    Mohan et al.

    Journal of Cell Biology, December 2018

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  • Type 9 secretion system structures reveal a new protein transport mechanism

    Lauber et al.

    Nature, November 2018

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  • Phenotypic consequences of RNA polymerase dysregulation in Escherichia coli

    Sarkar et al.

    Nucleic Acids Research, November 2017

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What our users are saying

"The Nanoimager provides our users with a powerful yet easy-to-use platform for super-resolution, single molecule localization imaging. The instrument is compact, intuitive to use and has been easy to integrate into our facility."

Dr Andrew Jefferson

Facility Manager at Micron Oxford, Advanced Bioimaging Unit

"While price was important for a new faculty like me, I am convinced I would have bought the Nanoimager if money had not been in question."

Dr Rizal F. Hariadi

Assistant Professor in Physics and faculty member at the Biodesign Institute, at Arizona State University.

"The ONI brings single molecule measurements out of the dark room and in to any research lab. The ONI is stable, sensitive and affordable allowing researchers to quickly get to grips with performing their measurements."

Dr. Chris Toseland

Research Fellow (MRC) at University of Kent

"Single molecule microscopy is in fact a game changer for us. The Nanoimager is extremely user-friendly and is operated in my lab by a PhD student."

Ramesh Wigneshweraraj

Professor of Molecular Microbiology at Imperial College London

"It is a very impactful tool to accelerate a drug discovery process."

Dr Maria M.Flocco

Astra Zeneca

"We really hope that what we are doing is going to be the foundation of new discoveries, a new understanding of better ways to diagnose and treat tumors."

Dr Dario Bressan

CRUK Cambridge Centre

Some of our users

Our customers are spread over 4 different continents, here is a selection of them

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